Tenacious D in The Pick of Destiny (2006)

The film does not feature any identifiable LGBTQ+ characters or themes. While the protagonists' intense male friendship includes comedic homoerotic subtext, it is not presented as an actual depiction of queer identity. Therefore, the film has no net impact on the portrayal of LGBTQ+.

The film primarily focuses on two male protagonists and their musical journey. No female characters are depicted engaging in or winning close-quarters physical combat against male opponents.

The film features the established male duo Tenacious D and introduces new supporting characters whose genders are not swapped from any prior canonical or historical representation. No existing characters are portrayed with a different gender.

The film is an original story for the band Tenacious D, featuring its real-life members Jack Black and Kyle Gass. All other significant characters are either new creations for the film or real individuals playing themselves, without any prior established racial canon that was altered.